Our new preprint about cerebellar function in larval zebrafish

Larval zebrafish can adapt their swimming behavior in response to changes in the environment in two ways. Firstly, they can adapt their behavior within a single swimming bout in response to unexpected changes in visual feedback they receive upon swimming. Secondly, they can adapt in a long-term manner if changes in feedback are consistent over a long period of time. By combining behavioral experiments with loss-of-function approach, modelling and whole-brain functional imaging, we show that the first type of adaptation is implemented by a feedback control mechanism that does not involve the cerebellum. However, if changes in the environment are consistent and predictable, they can update a cerebellar internal model. Cerebellum can then recalibrate the feedback controller so that the swimming behavior becomes adequate to the new environmental conditions. Read the full preprint here